Heterologous
collagen-hydrolyzed
bone graft
The best alternative to autologous bone
Bio-Gen® was among the first bone grafts to differentiate itself from the paradigm of the heterologous biomaterials produced by heat treatment. Obtained through an enzymatic process at controlled temperatures, Bio-Gen® keeps the mineral component completely unaltered, preserving bone collagen (type I collagen) in hydrolyzed form within it.
PROPERTIES
-
SUPERIOR
QUALITY
RAW MATERIAL -
ENZYMATIC
DEANTIGENATION -
UNALTERED
MINERAL
PHASE -
HYDROLYZED
COLLAGEN -
BETA RAY
STERILIZATION
BENEFITS
-
IT IS MORE
NATURAL -
INCREASED
PREDICTABILITY
OF RESULTS -
IT HAS AN IDEAL
STRUCTURE
The regenerative solution since 1995
Bio-Gen® is the bone graft used since 1995 by dentists and surgeons in more than 60 countries worldwide. Its clinical efficacy is demonstrated by more than 100 publications in national and international professional journals.
ALONGSIDE THE PRACTITIONER
IN EVERYDAY SURGERIES
Bio-Gen® is available in 3 convenient formats designed for the most common regenerative surgeries in the dental office: alveolar preservation, small guided bone regeneration (GBR), sinus lift, bone cyst filling.
THE RANGE
GRANULES • GRANULES IN SYRINGE • PUTTY
BIO-GEN® PROMOTES THE NATURAL
PROCESS OF BONE REGENERATION
Histologies of regenerated bone samples at 6 months after regenerative surgery, stained with hematoxylin-eosin: black arrows indicate the newly formed bone, squares the residual biomaterial. Note the large amount of newly formed bone and the perfect integration of Bio-Gen® granules, as well as the absence of inflammatory infiltrates.
University of Milan, Department of Biomedical, Surgical and Dental Sciences
Insights
Clinical and histological evidence
Bio-Gen® is a material that integrates physiologically with tissues, promoting the body’s regenerative potential. In an in vitro study on bone marrow stem cells1 Bio-Gen® has been shown to promote their differentiation into osteoprogenitor cells (osteoblasts) significantly more than anorganic bovine bone, which is produced by applying high temperatures and thus lacks collagen component.
Measurement of cell differentiation by quantification
of the enzyme Alkaline Phosphatase
The entire range
BIO-GEN®
Granules
| BGC-05s | Cortical Granules – 1 btl / 0.5g 0.25-1mm |
| BGS-05s | Cancellous Granules – 1 btl / 0.5g 0.25-1mm |
| BGS-09s | Cancellous Granules – 1 btl / 0.5g 1-2mm |
| BGS-11s | Cancellous Granules – 1 btl / 1g 1-2mm |
| BGS-20 | Cancellous Granules – 1 btl / 2g 0.25-1mm |
| BGS-22 | Cancellous Granules – 1 btl / 2g. 1-2mm. |
| BGS-23s | Cancellous Granules – 1 btl / 1g 2-3mm |
| BGM-05s | Cancellous Cortical Granules – 1 btl / 0.5g 0.25-1mm |
| BGM-100s | Cancellous Cortical Granules – 1 btl / 1g 0.25-1mm |
| BGM-10s | Cancellous Cortical Granules – 1 btl / 0.25g 0.25-1mm |
| BGM-20 | Cancellous Cortical Granules – 1 btl / 2g 0.25-1mm |
BIO-GEN®
Putty
| BGP-01s | Cancellous Dry Paste Putty – 1 btl / 0.5cc |
BIO-GEN®
Gel Granules
| BGM-GEL02n | Cancellous Cortical Gel – 1 syr / 0.25ml 0.25-1mm |
| BGM-GEL05s | Cancellous Cortical Gel – 1 syr / 0.5ml 0.25-1mm |
| BGM-GEL1s | Cancellous Cortical Gel – 1 syr / 1ml 0.25-1mm |
YOU CAN STILL DONATE BLOOD
Patients treated with all Bioteck medical devices remain suitable for the donation
of blood or blood components, as stated in current legislation.
